INFORMATION REGARDING CHLOROFORM

INFORMATION REGARDING CHLOROFORM, BROMOBENZENE,
AND GREAT LAKES CHEMICAL CORPORATION

http://toxnet.nlm.nih.gov/cgi-bin/sis/search/f?./temp/~5JBgJd:6
BROMOBENZENE
CASRN: 108-86-1

Atmospheric Concentrations :

SOURCE DOMINATE: Ambient air concns of bromobenzene were collected over a five day period (7/17/77 to 7/21/77) near Great Lakes Chemical Corp in El Dorodo, Arkansas. Twenty-one samples from five different locations were collected. Results showed that the levels of bromobenzene ranged from 5.3 ng/l (period 1, cycle 1, location 1) to 4,276 ng/l (period 3, cycle 1, location 3)(1). Ambient air concns of bromobenzene were collected over a two year period (1976 to 1977) near Great Lakes Chemical Corp in El Dorado, Arkansas and a one day period in 1977 in Magnolia, Arkansas. Concns in El Dorodo ranged from 4.8 ng/cu m to 4,276 ng/cu m. Concns in Magnolia ranged from 23 ng/cu m to 140 ng/cu m(2).
[(1) Pellizzari ED et al; Environmental Monitoring Near Industrial Sites: Brominated Chemicals Part I. Washington, DC: USEPA. Off Toxic Sub (1978) (2) Pellizzari ED, Bunch JE; Ambient Air Carcinogenic Vapors Improved Sampling and Analytical Techniques and Field Studies. USEPA Environ Sci Res Lab, Research Triangle Park,NC: USEPA-600/2-79-081 (NTIS PB-297 932) p.302 (1979)]**PEER REVIEWED**

Manufacturers :

Diaz Chemical Corporation, Hq, 40 Jackson Street, PO Box 194, Holley, NY 14470, (716) 638-6321 Production site: Holley, NY 14470
[SRI. 1995 Directory of Chemical Producers-United States of America. Menlo Park, CA: SRI International, 1995479]**PEER REVIEWED**

Solubilities :

MISCIBLE WITH CHLOROFORM, BENZENE, PETROLEUM HYDROCARBONS; SOL IN ALCOHOL (10.4 G/100 G @ 25 DEG C), IN ETHER (71.3 G/100 G @ 25 DEG C); PRACTICALLY INOL IN WATER (0.045 G/100 G @ 30 DEG C)
[Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989.213]**PEER REVIEWED**

Environmental Fate/Exposure Summary :

Bromobenzene's production and use as an additive to motor oil, in organic synthesis to make phenyl magnesium bromide, as a solvent for crystallization on a large scale, and where a heavy liquid is desirable may result in its release to the environment through various waste streams. If released to the the atmosphere, bromobenzene will exist in the vapor phase in the ambient atmosphere, based on a measured vapor pressure of 4.18 mm Hg at 25 deg C. Vapor-phase bromobenzene is degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals with a half-life of about 21 days. An estimated Koc value of 268 suggests that bromobenzene will have moderate mobility in soil. Volatilizaton from moist soil surfaces should occur based upon an experimental Henry's Law constant of 2.08X10-3 atm-cu m/mole. Volatilization from dry soil surfaces should be important given the vapor pressure of this compound. Bromobenzene is not biodegraded in screening studies using an activated sludge as inoculum; 0% degradation was reported after four weeks. In water, bromobenzene may adsorb to sediment or particulate matter based on its estimated Koc value of 268. This compound will volatilize from water surfaces given its experimental Henry's Law constant. Estimated half-lives for a model river and model lake are 4 hours and 5 days, respectively. Bioconcentration in aquatic organisms should be low to moderately high based on measured BCF values ranging from 8.8 to 190. Given the commercial uses of bromobenzene, human exposure appears to be likely from occupational situations through dermal and inhalation routes and consumer exposure to motor oil. Due to the compound's presence in food, ambient air, and finished water, general population exposure may be possible by ingestion and inhaltion routes. (SRC)
**PEER REVIEWED**

GREAT LAKES CHEMICAL CORPORATION AND THE PATHFINDERS CAMP